CROSSalive

Computes RNA secondary structure profile in vivo considering m6A and A-to-I effects.

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RNA Sequences (FASTA format, please ensure that your sequences only contain A, C, G, T, and U. Do not use !@#$% etc.; the minimum required sequence length is 70 nucleotides)


Just trying out? Use the following examples:

Profile of the RepC, a region of Xist mildly affected by METLL3, showing a Pearson’s correlation of 0.30 with in vivo SHAPE data (Smola et al. 2016)

Profile of the whole sequence of NEAT1, a lincRNA whose structural profile was studied in presence of ADAR showing a AUC of 0.85 with PARS data (Solomon et al. 2017)