Tutorial: Using the RIME Web Server

Overview

Welcome to the RIME Web Service. This service allows users to predict RNA-RNA interactions solely from sequence information. Starting from two long RNA sequences, the application calculates RIMEfull prediction scores for 200x200 nucleotides windows with a 100 nucleotides step. This tutorial will guide you through the steps of using the web service, from inputting your data to retrieving your results

Step-by-Step Instructions

Step 1: Accessing the Web Server

Step 2: Inputting Your Data

You can input your data in one of the following ways:

  • Text submission:
    • Scroll down to the input window labeled "Text submission".
    • Type or paste your two RNA sequences in the FASTA format.
    • Example Image

  • File submission:
    • Click on the "File submission" button.
    • Select 2 files from your computer. Each file should be a FASTA.
    • Example Image

Step 3:Submitting Your Data

  • Submit:
    • Click the "Submit" button to start the analysis process.
    • You will be redirected to a page that confirms your submission and provides a tracking ID (web link).

Step 4: Retrieving Your Results

  • Notification:
    • If you provided an email address, you will receive an email with a link to your results once the analysis is complete
  • Download Results:
    • Click on the provided link to access your results.
    • Table View: Navigate to the Table tab to view a detailed table displaying RIMEfull prediction scores across all 200x200 nucleotide windows. The same table can be downloaded in BEDPE format by clicking on the “Get table” button.
    • Plot View: Switch to the Plot tab to visualize the same data as a heatmap for an intuitive representation of the results.